CORE FACILITIES: Metabolomics

Services

The aim of the Metabolomics Core Facility is to assists all scientists to successfully set-up their metabolomics research projects.
Since each organism contains a wide range of functionally and chemically diverse metabolites, with different physico-chemical properties, different analytical approaches are required for their efficient analysis. Accordingly, we offer, depending on the individual demands, different levels of support. On the one hand, we can offer routine qualitative and quantitative gas- and liquid-chromatography separation methods, in combination to a wide range of high and low resolution mass spectrometers. These methods allow for the basic analysis of polar metabolites from the central metabolism, next to the qualitative analysis of a comprehensive inventory of cellular lipids.
In case more complex, especially untargeted or larger scale studies are requested or the analysis of specific metabolites is demanded, we can support the scientists at the level of the experimental design, the set-up of specific sample preparation and metabolite extraction methods but also at the level of data analysis, visualization and interpretation.
Our main goal is to be in close cooperation with the scientific research groups and provide flexible, fast and reliable service, to users' requests to answer and elucidate biological questions.

Instruments

  • Waters TQ coupled to Thermo Fisher Dionex™ ICS-5000+

  • Waters TQ-S coupled to Acquity UPLC (iClass)

  • Thermo Fisher Exactive HF coupled to Acquity UPLC (iClass)

  • Thermo Fisher Q Exactive GC Orbitra GC-MS/MS