Publications

Nuechel, J.; Omidi, M.; Fernandes, S. A.; Tauber, M.; Pohl, S.; Plomann, M.; Demetriades, C.: GRASP55 maintains lysosome function by controlling sorting of lysosomal enzymes at the Golgi. EMBO Reports (2026)

Dauben, H.; Mihaljevic, M.; Kolvenbach, A.; Palumbieri, M. D.; Kapsali, C.; Huppertz, I.; Matić, I.: Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling. Nature Communications 17, 3216 (2026)

Smulders, L.; Mak, J. K. L.; Hägg, S.; Deelen, J.: The MetaboHealth score is 40% heritable and is influenced by frailty status, BMI, and smoking in Swedish twins. GeroScience (2026)

Nishigori, M.; Hirata, S.; Kosako, H.; Ichinohe, T.; Nolte, H.; Riemer, J.; Langer, T.; Koshiba, T.: Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity. The EMBO Journal (2026)

Morabito, G.; Dönertas, H. M.; Sperti, L.; Seidel, J.; Poursadegh Zonouzi, A.; Poeschla, M.; Valenzano, D. R.: Spontaneous aging-associated inflammation and genome instability in the immune system of turquoise killifish. Nature Aging 6, pp. 665 - 681 (2026)

Kroczek, L.; Nolte, H.; Lasarzewski, Y.; Agrawal, I.; Molinié, T.; Curbelo Piñero, D.; Lemke, K.; Rugarli, E.; Langer, T.: Stress adaptation of mitochondrial protein import by OMA1-mediated degradation of DNAJC15. Nature Structural & Molecular Biology (2026)

Steiger, M.; Singh, N.; Tyers, A. M.; Kretzmer, H.; Valenzano, D. R.; Meissner, A.: The DNA methylation landscape of naturally short-lived killifish. Scientific Reports 16, 7173 (2026)

Köhler, D.; Kleinenkuhnen, N.; Rastegar, K.; Baar, T.; Nikopoulou, C.; Kondylis, V.; Milchevskaya, V.; Schmid, M.; Tessarz, P.; Tresch, A.: A spectral dimension reduction technique that improves pattern detection in multivariate spatial data. Bioinformatics (2026)

Köhler, D.; Kleinenkuhnen, N.; Rastegar, K.; Baar, T.; Nikopoulou, C.; Kondylis, V.; Milchevskaya, V.; Schmid, M.; Tessarz, P.; Tresch, A.: A spectral dimension reduction technique that improves pattern detection in multivariate spatial data. Bioinformatics (2026)

Morwani‐Mangnani, J.; Bogaards, F. A.; Umanets, A.; Hul, G. B.; Gijbels, A.; Goossens, G. H.; Deelen, J.; Beekman, M.; Afman, L.; Blaak, E. E. et al.; Slagboom, P. E.: TheMetaboHealthScore Enhances Insulin Resistance Metabotyping for Targeted Fat Loss: ThePERSONStudy. Obesity (2026)

Daniel, K.; Ullrich, L.; Ruchnewitz, D.; Meijers, M.; Halwe, N. J.; Wild, U.; Eberhardt, J.; Schön, J.; Stumpf, R.; Schlotz, M. et al.; Wunsch, M.; Girao Lessa, L.; Abdelwhab, E. M.; Kuryshko, M.; Dietrich, C.; Pinger, A.; Schumacher, A. L.; Germer, M.; Rohde, M.; Kukat, C.; Gieselmann, L.; Gruell, H.; Hoffmann, D.; Beer, M.; Erren, T.; Lässig, M.; Kreer, C.; Klein, F.: Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed individuals. Immunity 59, pp. 494 - 508.e8 (2026)

Henrich, A.; Scheiblich, H.: Mobile Powerhouses: Mitochondria Transfer via Tunnelling Nanotubes in Brain Health and Neurodegenerative Diseases. European Journal of Neuroscience 63 (2026)

Kroczek, L.; Langer, T.: Proteolytic control of mitochondrial protein translocases. Protein Science 35 (2026)

Morwani‐Mangnani, J.; Bogaards, F. A.; Umanets, A.; Hul, G. B.; Gijbels, A.; Goossens, G. H.; Deelen, J.; Beekman, M.; Afman, L.; Blaak, E. E. et al.; Slagboom, P. E.: TheMetaboHealthScore Enhances Insulin Resistance Metabotyping for Targeted Fat Loss: ThePERSONStudy. Obesity 34, pp. 550 - 564 (2026)

Rack, J. G. M.; Prokhorova, E.; Lauro, R.; Kopasz, A. G.; Baretić, D.; Raggiaschi, R.; Mutabdzija, J.; Filippov, D. V.; Timinszky, G.; Leidecker, O. et al.; Ahel, I.; Palazzo, L.: Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity. Open Biology 16 (2026)

Zhang, R.; Huetzen, M. A.; Binici, A.; Martín-Gago, P.; Gasper, R.; Rudashevskaya, E.; Liu, J.; Nagaraju, C.; Reckzeh, E. S.; Stuedle, A. S. T. et al.; Hopff, A.-S.; Mesaros, A.; Unger, A.; Thelen, M.; Janning, P.; Reinhardt, H. C.; Ziegler, S.; Jachimowicz, R. D.; Waldmann, H.: Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling. Journal of Medicinal Chemistry 69, pp. 964 - 981 (2026)

Müller-Limberger, E.; Frederick, B.; Hansen, S.; Wohlfarth, M.; Kasper, P.; Janoschek, R.; Mahabir, E.; Fischer, P.; Mesaros, A.; Purrio, M. et al.; Quaas, A.; Alejandre Alcázar, M. A.; Dötsch, J.; Hucklenbruch-Rother, E.; Appel, S.: Metformin in Obese Pregnancy: Developmental Reprogramming of Offspring Liver and MASLD Risk by Age and Sex. Endocrinology (2025)

Campos-Ribeiro, M. A.; Donnarumma, E.; Nolte, H.; Cobine, P.; Vimont, E.; Milenkovic, D.; Hernandez-Camacho, J. D.; Langa-Vives, F.; Kornobis, E.; Pénard, E. et al.; Yde, S.; Langer, T.; Paquis-Flucklinger, V.; Wai, T.: Mutant CHCHD10 disrupts cytochrome c oxidation and activates mitochondrial retrograde signaling. EMBO Molecular Medicine (2025)

Casanueva Reimon, L.; Gouveia, A.; Carvalho, A.; Schmehr, J. N.; El Mehdi, M.; Moreira-Soto, R. D.; Ardanaz, C. G.; Bulk, J.; Rigoux, L.; Klemm, P. et al.; Cremer, A. L.; Dethloff, F.; Hinze, Y.; Backes, H.; Giavalisco, P.; Steculorum, S. M.: Fat sensory cues in early life program central response to food and obesity. Nature Metabolism (2025)

Mehra, C.; Alvarado Valverde, J.; Matias, A. M. N.; Torelli, F.; Medeiros, T. C.; Straub, J.; Asaki, J. D.; Bradley, P. J.; Luck, K.; Lawo, S. et al.; Treeck, M.; Pernas, L.: Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection. Nature Microbiology 10, pp. 3331 - 3345 (2025)