Mitochondria are dynamic metabolic organelles that participate in cellular signaling and adapt to varying physiological demands. The activity of mitochondria declines with age and a dysfunction of these organelles is associated with numerous age-associated diseases, raising the question: how do mitochondria influence cell fitness and ageing?The department seeks to define molecular mechanisms that preserve mitochondrial function with age and drive the dynamic adaptation of the mitochondrial proteome in a cell- and tissue-specific manner. Projects focus on the function of mitochondrial proteases that are emerging as central regulators and orchestrate complex interactions of mitochondria with their cellular environment.
- 2021-2024 | German Research Council
Collaborative Research Center 1218: Mitochondrial Regulation of Cellular Function.
- 2020-2023 | German Research Council
Collaborative Research Center 1403: Cell Death in Immunity, Inflammation and Disease.
- 2020-2023 | German-Israel-Project MitoBalance
- Postdoctoral fellowships Humboldt Foundation, EMBO, Japanese Science Foundation