Publications

Department Partridge

Journal Article (18)

2017
Journal Article
Augustin, H.; Adcott, J.; Elliott, C. J. H.; Partridge, L.: Complex Roles of Myoglianin in Regulating Adult Performance and Lifespan. Fly (Austin), p. 0 (2017)
Journal Article
Augustin, H.; McGourty, K.; Allen, M. J.; Madem, S. K.; Adcott, J.; Kerr, F.; Wong, C. T.; Vincent, A.; Godenschwege, T.; Boucrot, E. et al.; Partridge, L.: Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. PLoS Biol 15 (9), p. e2001655 (2017)
Journal Article
Augustin, H.; McGourty, K.; Steinert, J. R.; Cocheme, H. M.; Adcott, J.; Cabecinha, M.; Vincent, A.; Halff, E. F.; Kittler, J. T.; Boucrot, E. et al.; Partridge, L.: Myostatin-like proteins regulate synaptic function and neuronal morphology. Development 144 (13), pp. 2445 - 2455 (2017)
Journal Article
Bolukbasi, E.; Khericha, M.; Regan, J. C.; Ivanov, D. K.; Adcott, J.; Dyson, M. C.; Nespital, T.; Thornton, J. M.; Alic, N.; Partridge, L.: Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Rep 21 (3), pp. 641 - 653 (2017)
Journal Article
Brandt, T.; Mourier, A.; Tain, L. S.; Partridge, L.; Larsson, N.G.; Kuhlbrandt, W.: Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. Elife 6 (2017)
Journal Article
Bustos, V.; Partridge, L.: Good Ol' Fat: Links between Lipid Signaling and Longevity. Trends Biochem Sci 42 (10), pp. 812 - 823 (2017)
Journal Article
Gorsky, M. K.; Burnouf, S.; Sofola-Adesakin, O.; Dols, J.; Augustin, H.; Weigelt, C. M.; Grönke, S.; Partridge, L.: Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity. Sci Rep 7 (1), p. 9984 (2017)
Journal Article
Hahn, O.; Grönke, S.; Stubbs, T. M.; Ficz, G.; Hendrich, O.; Krueger, F.; Andrews, S.; Zhang, Q.; Wakelam, M. J.; Beyer, A. et al.; Reik, W.; Partridge, L.: Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biol 18 (1), p. 56 (2017)
Journal Article
Kennedy, B. K.; Partridge, L.: 2nd interventions in aging conference. Aging (Albany NY) 9 (4), pp. 1090 - 1095 (2017)
Journal Article
Kerr, F.; Sofola-Adesakin, O.; Ivanov, D. K.; Gatliff, J.; Gomez Perez-Nievas, B.; Bertrand, H. C.; Martinez, P.; Callard, R.; Snoeren, I.; Cocheme, H. M. et al.; Adcott, J.; Khericha, M.; Castillo-Quan, J. I.; Wells, G.; Noble, W.; Thornton, J.; Partridge, L.: Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease. PLoS Genet 13 (3), p. e1006593 (2017)
Journal Article
Mizielinska, S.; Ridler, C. E.; Balendra, R.; Thoeng, A.; Woodling, N. S.; Grasser, F. A.; Plagnol, V.; Lashley, T.; Partridge, L.; Isaacs, A. M.: Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration. Acta Neuropathol Commun 5 (1), p. 29 (2017)
Journal Article
Moens, T. G.; Partridge, L.; Isaacs, A. M.: Genetic models of C9orf72: what is toxic? Curr Opin Genet Dev 44, pp. 92 - 101 (2017)
Journal Article
Niccoli, T.; Partridge, L.; Isaacs, A. M.: Ageing as a risk factor for ALS/FTD. Hum Mol Genet 26 (R2), pp. R105 - R113 (2017)
Journal Article
Piper, M. D.; Soultoukis, G. A.; Blanc, E.; Mesaros, A.; Herbert, S. L.; Juricic, P.; He, X.; Atanassov, I.; Salmonowicz, H.; Yang, M. et al.; Simpson, S. J.; Ribeiro, C.; Partridge, L.: Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metab 25 (3), pp. 610 - 621 (2017)
Journal Article
Tain, L. S.; Sehlke, R.; Jain, C.; Chokkalingam, M.; Nagaraj, N.; Essers, P.; Rassner, M.; Grönke, S.; Froelich, J.; Dieterich, C. et al.; Mann, M.; Alic, N.; Beyer, A.; Partridge, L.: A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Mol Syst Biol 13 (9), p. 939 (2017)
Journal Article
Tiku, V.; Jain, C.; Raz, Y.; Nakamura, S.; Heestand, B.; Liu, W.; Spath, M.; Suchiman, H. E. D.; Muller, R. U.; Slagboom, P. E. et al.; Partridge, L.; Antebi, A.: Small nucleoli are a cellular hallmark of longevity. Nat Commun 8, p. 16083 (2017)
Journal Article
Zhao, Y.; Gilliat, A. F.; Ziehm, M.; Turmaine, M.; Wang, H.; Ezcurra, M.; Yang, C.; Phillips, G.; McBay, D.; Zhang, W. B. et al.; Partridge, L.; Pincus, Z.; Gems, D.: Two forms of death in ageing Caenorhabditis elegans. Nat Commun 8, p. 15458 (2017)
Journal Article
Ziehm, M.; Kaur, S.; Ivanov, D. K.; Ballester, P. J.; Marcus, D.; Partridge, L.; Thornton, J. M.: Drug repurposing for aging research using model organisms. Aging Cell 16 (5), pp. 1006 - 1015 (2017)
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