Publications of Marie-Lune Simard

Burr, S. P.; Klimm, F.; Glynos, A.; Prater, M.; Sendon, P.; Nash, P.; Powell, C. A.; Simard, M.-L.; Bonekamp, N. A.; Charl, J. et al.; Diaz, H.; Bozhilova, L. V.; Nie, Y.; Zhang, H.; Frison, M.; Falkenberg, M.; Jones, N.; Minczuk, M.; Stewart, J. B.; Chinnery, P. F.: Cell lineage-specific mitochondrial resilience during mammalian organogenesis. Cell (2023)

Milenkovic, D.; Sanz-Moreno, A.; Calzada-Wack, J.; Rathkolb, B.; Veronica Amarie, O.; Gerlini, R.; Aguilar-Pimentel, A.; Misic, J.; Simard, M.-L.; Wolf, E. et al.; Fuchs, H.; Gailus-Durner, V.; de Angelis, M. H.; Larsson, N.G.: Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction. PLoS Genet 18 (5), p. e1010190 (2022)

Gammage, P. A.; Viscomi, C.; Simard, M.-L.; Costa, A. S. H.; Gaude, E.; Powell, C. A.; Van Haute, L.; McCann, B. J.; Rebelo-Guiomar, P.; Cerutti, R. et al.; Zhang, L.; Rebar, E. J.; Zeviani, M.; Frezza, C.; Stewart, J.; Minczuk, M.: Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nat Med 24 (11), pp. 1691 - 1695 (2018)

Matic, S.; Jiang, M.; Nicholls, T. J.; Uhler, J. P.; Dirksen-Schwanenland, C.; Polosa, P. L.; Simard, M.-L.; Li, X.; Atanassov, I.; Rackham, O. et al.; Filipovska, A.; Stewart, J.; Falkenberg, M.; Larsson, N.G.; Milenkovic, D.: Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9 (1), p. 1202 (2018)

Simard, M.-L.; Mourier, A.; Greaves, L. C.; Taylor, R. W.; Stewart, J.: A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol 245 (3), pp. 311 - 323 (2018)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep 16 (11), pp. 2980 - 90 (2016)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell reports 16 (11), pp. 2980 - 2990 (2016)