Publications of T. Langer

Nolden, M.; Kisters-Woike, B.; Langer, T.; Graef, M.: Quality control in the mitochondrion. Topics in Current Genetics 16, pp. 119 - 147 (2006)

Nolden, M.; Ehses, S.; Koppen, M.; Bernacchia, A.; Rugarli, E. I.; Langer, T.: The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell 123 (2), pp. 277 - 89 (2005)

Kambacheld, M.; Augustin, S.; Tatsuta, T.; Muller, S.; Langer, T.: Role of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria. J Biol Chem 280 (20), pp. 20132 - 9 (2005)

Nolden, M.; Ehses, S.; Koppen, M.; Bernacchia, A.; Rugarli, E. I.; Langer, T.: The m-AAA Protease Defective in Hereditary Spastic Paraplegia Controls Ribosome Assembly in Mitochondria. Cell 123, pp. 277 - 289 (2005)

Augustin, S.; Nolden, M.; Muller, S.; Hardt, O.; Arnold, I.; Langer, T.: Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux. J Biol Chem 280 (4), pp. 2691 - 9 (2004)

Tatsuta, T.; Model, K.; Langer, T.: Formation of membrane-bound ring complexes by prohibitins in mitochondria. Mol Biol Cell 16 (1), pp. 248 - 59 (2004)

Galluhn, D.; Langer, T.: Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 279 (37), pp. 38338 - 45 (2004)

Korbel, D.; Wurth, S.; Kaser, M.; Langer, T.: Membrane protein turnover by the m-AAA protease in mitochondria depends on the transmembrane domains of its subunits. EMBO Rep 5 (7), pp. 698 - 703 (2004)

Atorino, L.; Silvestri, L.; Koppen, M.; Cassina, L.; Ballabio, A.; Marconi, R.; Langer, T.; Casari, G.: Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol 163 (4), pp. 777 - 87 (2003)

Kaser, M.; Kambacheld, M.; Kisters-Woike, B.; Langer, T.: Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease. J Biol Chem 278 (47), pp. 46414 - 23 (2003)

Arnold, I.; Langer, T.: Membrane protein degradation by AAA proteases in mitochondria. Biochim Biophys Acta 1592 (1), pp. 89 - 96 (2002)

Klanner, C.; Prokisch, H.; Langer, T.: MAP-1 and IAP-1, two novel AAA proteases with catalytic sites on opposite membrane surfaces in mitochondrial inner membrane of Neurospora crassa. Mol Biol Cell 12 (9), pp. 2858 - 69 (2001)

Young, L.; Leonhard, K.; Tatsuta, T.; Trowsdale, J.; Langer, T.: Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291 (5511), pp. 2135 - 8 (2001)

Krzewska, J.; Langer, T.; Liberek, K.: Mitochondrial Hsp78, a member of the Clp/Hsp100 family in Saccharomyces cerevisiae, cooperates with Hsp70 in protein refolding. FEBS Lett 489 (1), pp. 92 - 6 (2001)

Van Dyck, L.; Langer, T.: ATP-dependent proteases controlling mitochondrial function in the yeast Saccharomyces cerevisiae. Cell Mol Life Sci 56 (9-10), pp. 825 - 42 (2001)

Langer, T.: Export von Peptiden aus Mitochondrien – ein neuer intrazellulärer Transportweg. Biologie in unserer Zeit 5, pp. 330 - 331 (2001)

Langer, T.; Käser, M.; Klanner, C.; Leonhard, K.: AAA proteases of mitochondria: quality control of membrane proteins and regulatory functions during mitochondrial biogenesis. Biochemical Society Transactions 29, pp. 431 - 436 (2001)

Rapaport, D.; Taylor, R. D.; Käser, M.; Langer, T.; Neupert, W.; Nargang, F. E.: Structural Requirements of Tom40 for Assembly into Preexisting TOM Complexes of Mitochondria. Molecular Biology of the Cell 12, pp. 1189 - 1198 (2001)

Kaser, M.; Langer, T.: Protein degradation in mitochondria. Semin Cell Dev Biol 11 (3), pp. 181 - 90 (2000)

Leonhard, K.; Guiard, B.; Pellecchia, G.; Tzagoloff, A.; Neupert, W.; Langer, T.: Membrane protein degradation by AAA proteases in mitochondria: extraction of substrates from either membrane surface. Mol Cell 5 (4), pp. 629 - 38 (2000)