Publications

Erdinc, D.; Albus, C. A.; Rodriguez-Luis, A.; Menger, K. E.; Thorsell, A.; Atanassov, I.; Rovsnik, U.; Falkenberg, M.; Gustafsson, C. M.; Nicholls, T. J. J.: Proteolytic cleavage activates the mitochondrial isoform of TOP3A. Nucleic Acids Res. (2025)

Laboy, R.; Ndoci, M.; Syed, S. T.; Vonolfen, M.; Ballhysa, E.; Droth, T.; Schilling, K.; Löhrke, A.; Atanassov, I.; Antebi, A.: Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics. eLife 12 (2025)

Glasgow, R. I. C.; Singh, V.; Peña-Pérez, L.; Wilhalm, A.; Moedas, M. F.; Moore, D.; Rosenberger, F. A.; Li, X.; Atanassov, I.; Saba, M. et al.; Cipullo, M.; Rorbach, J.; Wedell, A.; Freyer, C.; Amunts, A.; Wredenberg, A.: The mitochondrial methylation potential gates mitoribosome assembly. Nature Communications 16, 5388 (2025)

Busch, J.; Schöndorf, T.; Milenkovic, D.; Li, X.; Wibom, R.; Silva-Rodrigues, J. F.; Filograna, R.; Koolmeister, C.; Larsson, N.-G.; Rubalcava-Gracia, D.: The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly. Mitochondrion, 102099, p. 102099 (2025)

Miranda, M.; Mesaros, A.; Scrima, N.; Pérard, L.; Kuznetsova, I.; Purrio, M.; Atanassov, I.; Filipovska, A.; Mourier, A.; Larsson, N.-G. et al.; Kühl, I.: POLRMT overexpression increases mtDNA transcription without affecting steady-state mRNA levels. Life Science Alliance 8, p. e202302563 (2025)

Mukherjee, R.; Bhattacharya, A.; Mello-Vieira, J.; Kuncha, S. K.; Hoffmann, M.; Gonzalez, A.; Rathore, R.; Chadha, A.; Shin, D.; Colby, T. et al.; Matić, I.; Mukherjee, S.; Misra, M.; Dikic, I.: Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis. Autophagy (2024)

Cipullo, M.; Valentín Gesé, G.; Gopalakrishna, S.; Krueger, A.; Lobo, V.; Pirozhkova, M. A.; Marks, J.; Páleníková, P.; Shiriaev, D.; Liu, Y. et al.; Misic, J.; Cai, Y.; Nguyen, M. D.; Abdelbagi, A.; Li, X.; Minczuk, M.; Hafner, M.; Benhalevy, D.; Sarshad, A. A.; Atanassov, I.; Hällberg, B. M.; Rorbach, J.: GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature Communications 15, 5664 (2024)

Kim, J. Y.; Atanassov, I.; Dethloff, F.; Kroczek, L.; Langer, T.: Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria. Life science alliance 6 (9), e202302127 (2023)

Remes , C.; Khawaja, A.; Pearce, S. F.; Dinan, A. M.; Gopalakrishna, S.; Cipullo, M.; Kyriakidis, V.; Zhang, J.; Dopico, X. C.; Yukhnovets, O. et al.; Atanassov, I.; Firth, A. E.; Cooperman, B.; Rorbach, J.: Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria. Nucleic Acids Research (2023)

Krüger, A.; Remes, C.; Shiriaev, D. I.; Liu, Y.; Spåhr, H.; Wibom, R.; Atanassov, I.; Nguyen, M. D.; Cooperman, B. S.; Rorbach, J.: Human mitochondria require mtRF1 for translation termination at non-canonical stop codons. Nature Communications 14, 30 (2023)

Milenkovic, D.; Misic, J.; Hevler, J. F.; Molinié, T.; Chung, I.; Atanassov, I.; Li, X.; Filograna, R.; Mesaros, A.; Mourier, A. et al.; Heck, A. J.R.; Hirst, J.; Larsson, N.-G.: Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes. Cell Metabolism (2023)

Itoh, Y.; Khawaja, A.; Laptev, I.; Cipullo, M.; Atanassov, I.; Sergiev, P.; Rorbach, J.; Amunts, A.: Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606 (7914), pp. 603 - 608 (2022)

Li, X.; Straub, J.; Medeiros, T. C.; Mehra, C.; den Brave, F.; Peker, E.; Atanassov, I.; Stillger, K.; Michaelis, J. B.; Burbridge, E. et al.; Adrain, C.; Munch, C.; Riemer, J.; Becker, T.; Pernas, L.: Mitochondria shed their outer membrane in response to infection-induced stress. Science 375 (6577), p. eabi4343 (2022)

Bonekamp, N.; Jiang, M.; Motori, E.; Garcia Villegas, R.; Koolmeister, C.; Atanassov, I.; Mesaros, A.; Park, C. B.; Larsson, N.G.: High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo. Life Sci Alliance 4 (11), p. e202101034 (2021)

Koester, J.; Miroshnikova, Y. A.; Ghatak, S.; Chacón-Martínez, C. A.; Morgner, J.; Li, X.; Atanassov, I.; Altmuller, J.; Birk, D. E.; Koch, M. et al.; Bloch, W.; Bartusel, M.; Niessen, C. M.; Rada-Iglesias, A.; Wickström, S. A.: Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol 23 (7), pp. 771 - 781 (2021)

Jiang, M.; Xie, X.; Zhu, X.; Jiang, S.; Milenkovic, D.; Misic, J.; Shi, Y.; Tandukar, N.; Li, X.; Atanassov, I. et al.; Jenninger, L.; Hoberg, E.; Albarran-Gutierrez, S.; Szilagyi, Z.; Macao, B.; Siira, S. J.; Carelli, V.; Griffith, J. D.; Gustafsson, C. M.; Nicholls, T. J.; Filipovska, A.; Larsson, N.G.; Falkenberg, M.: The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Sci Adv 7 (27), p. eabf8631 (2021)

Miroshnikova, Y. A.; Manet, S.; Li, X.; Wickström, S. A.; Faurobert, E.; Albiges-Rizo, C.: Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell 32 (18), pp. 1724 - 1736 (2021)

Tain, L.; Sehlke, R.; Meilenbrock, R. L.; Leech, T.; Paulitz, J.; Chokkalingam, M.; Nagaraj, N.; Grönke, S.; Fröhlich, J.; Atanassov, I. et al.; Mann, M.; Beyer, A.; Partridge, L.: Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife 10 (2021)

Ruegenberg, S.; Mayr, F. A. M.C.; Atanassov, I.; Baumann, U.; Denzel, M.: Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun 12 (1), p. 2176 (2021)

Schober, F. A.; Atanassov, I.; Moore, D.; Calvo-Garrido, J.; Moedas, M. F.; Wedell, A.; Freyer, C.; Wredenberg, A.: Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits. Mol Cell Proteomics 20, p. 100065 (2021)