Publications of T. Langer

Koppen, M.; Bonn, F.; Ehses, S.; Langer, T.: Autocatalytic processing of m-AAA protease subunits in mitochondria. Mol Biol Cell 20 (19), pp. 4216 - 24 (2009)

Tondera, D.; Grandemange, S.; Jourdain, A.; Karbowski, M.; Mattenberger, Y.; Herzig, S.; Da Cruz, S.; Clerc, P.; Raschke, I.; Merkwirth, C. et al.; Ehses, S.; Krause, F.; Chan, D. C.; Alexander, C.; Bauer, C.; Youle, R.; Langer, T.; Martinou, J. C.: SLP-2 is required for stress-induced mitochondrial hyperfusion. EMBO J 28 (11), pp. 1589 - 600 (2009)

Osman, C.; Haag, M.; Potting, C.; Rodenfels, J.; Dip, P. V.; Wieland, F. T.; Brugger, B.; Westermann, B.; Langer, T.: The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184 (4), pp. 583 - 96 (2009)

Merkwirth, C.; Langer, T.: Mitofusin 2 builds a bridge between ER and mitochondria. Cell 135 (7), pp. 1165 - 7 (2008)

Merkwirth, C.; Langer, T.: Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta 1793 (1), pp. 27 - 32 (2008)

Tatsuta, T.; Langer, T.: Studying proteolysis within mitochondria. Methods Mol Biol 372, pp. 343 - 60 (2008)

Merkwirth, C.; Dargazanli, S.; Tatsuta, T.; Geimer, S.; Lower, B.; Wunderlich, F. T.; von Kleist-Retzow, J. C.; Waisman, A.; Westermann, B.; Langer, T.: Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev 22 (4), pp. 476 - 88 (2008)

Tatsuta, T.; Langer, T.: Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 27 (2), pp. 306 - 14 (2008)

Duvezin-Caubet, S.; Koppen, M.; Wagener, J.; Zick, M.; Israel, L.; Bernacchia, A.; Jagasia, R.; Rugarli, E. I.; Imhof, A.; Neupert, W. et al.; Langer, T.; Reichert, A. S.: OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell 18 (9), pp. 3582 - 90 (2007)

Koppen, M.; Langer, T.: Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases. Crit Rev Biochem Mol Biol 42 (3), pp. 221 - 42 (2007)

Graef, M.; Seewald, G.; Langer, T.: Substrate recognition by AAA+ ATPases: distinct substrate binding modes in ATP-dependent protease Yme1 of the mitochondrial intermembrane space. Mol Cell Biol 27 (7), pp. 2476 - 85 (2007)

Tatsuta, T.; Augustin, S.; Nolden, M.; Friedrichs, B.; Langer, T.: m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria. EMBO J 26 (2), pp. 325 - 35 (2007)

Osman, C.; Wilmes, C.; Tatsuta, T.; Langer, T.: Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase. Mol Biol Cell 18 (2), pp. 627 - 35 (2006)

Koppen, M.; Metodiev, M. D.; Casari, G.; Rugarli, E. I.; Langer, T.: Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia. Mol Cell Biol 27 (2), pp. 758 - 67 (2006)

Durr, M.; Escobar-Henriques, M.; Merz, S.; Geimer, S.; Langer, T.; Westermann, B.: Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. Mol Biol Cell 17 (9), pp. 3745 - 55 (2006)

Escobar-Henriques, M.; Westermann, B.; Langer, T.: Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1. J Cell Biol 173 (5), pp. 645 - 50 (2006)

Escobar-Henriques, M.; Langer, T.: Mitochondrial shaping cuts. Biochim Biophys Acta 1763 (5-6), pp. 422 - 9 (2006)

Rugarli, E. I.; Langer, T.: Translating m-AAA protease function in mitochondria to hereditary spastic paraplegia. Trends Mol Med 12 (6), pp. 262 - 9 (2006)

Graef, M.; Langer, T.: Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement. J Struct Biol 156 (1), pp. 101 - 8 (2006)

Arnold, I.; Wagner-Ecker, M.; Ansorge, W.; Langer, T.: Evidence for a novel mitochondria-to-nucleus signalling pathway in respiring cells lacking i-AAA protease and the ABC-transporter Mdl1. Gene 367, pp. 74 - 88 (2006)