Publications of T. Langer

Langer, T.: AAA proteases: cellular machines for degrading membrane proteins. Trends Biochem Sci 25 (5), pp. 247 - 51 (2000)

Klanner, C.; Neupert, W.; Langer, T.: The chaperonin-related protein Tcm62p ensures mitochondrial gene expression under heat stress. FEBS Lett 470 (3), pp. 365 - 9 (2000)

Steglich, G.; Neupert, W.; Langer, T.: Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria. Mol Cell Biol 19 (5), pp. 3435 - 42 (1999)

Leonhard, K.; Stiegler, A.; Neupert, W.; Langer, T.: Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398 (6725), pp. 348 - 51 (1999)

van Dyck, L.; Dembowski, M.; Neupert, W.; Langer, T.: Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae. FEBS Lett 438 (3), pp. 250 - 4 (1998)

Arlt, H.; Steglich, G.; Perryman, R.; Guiard, B.; Neupert, W.; Langer, T.: The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease. EMBO J 17 (16), pp. 4837 - 47 (1998)

Savel'ev, A. S.; Novikova, L. A.; Kovaleva, I. E.; Luzikov, V. N.; Neupert, W.; Langer, T.: ATP-dependent proteolysis in mitochondria. m-AAA protease and PIM1 protease exert overlapping substrate specificities and cooperate with the mtHsp70 system. J Biol Chem 273 (32), pp. 20596 - 602 (1998)

van Dyck , L.; Neupert , W.; Langer, T.: The ATP-dependent PIM1 protease is required for the expression of intron-containing genes in mitochondria. Genes Dev 12 (10), pp. 1515 - 24 (1998)

Bergeron, J. J.; Craig, E. A.; Horwich, A. L.; Langer, T.; Multhoff, G.; Smith, D. F.; Hightower, L. E.: Molecular chaperones in biology and medicine at Obernai. Cell Stress Chaperones 2 (4), pp. 220 - 8 (1998)

Wagner, I.; van Dyck, L.; Savel'ev, A. S.; Neupert, W.; Langer, T.: Autocatalytic processing of the ATP-dependent PIM1 protease: crucial function of a pro-region for sorting to mitochondria. EMBO J 16 (24), pp. 7317 - 25 (1998)

Langer, T.; Neupert, W.: Regulated protein degradation in mitochondria. Experientia 52 (12), pp. 1069 - 76 (1996)

Stuart, R. A.; Ono, H.; Langer, T.; Neupert, W.: Mechanisms of protein import into mitochondria. Cell Struct Funct 21 (5), pp. 403 - 6 (1996)

Schmitt, M.; Neupert, W.; Langer, T.: The molecular chaperone Hsp78 confers compartment-specific thermotolerance to mitochondria. J Cell Biol 134 (6), pp. 1375 - 86 (1996)

Leonhard, K.; Herrmann, J. M.; Stuart, R. A.; Mannhaupt, G.; Neupert, W.; Langer, T.: AAA proteases with catalytic sites on opposite membrane surfaces comprise a proteolytic system for the ATP-dependent degradation of inner membrane proteins in mitochondria. EMBO J 15 (16), pp. 4218 - 29 (1996)

Arlt, H.; Tauer, R.; Feldmann, H.; Neupert, W.; Langer, T.: The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 85 (6), pp. 875 - 85 (1996)

Teichmann, U.; van Dyck, L.; Guiard, B.; Fischer, H.; Glockshuber, R.; Neupert, W.; Langer, T.: Substitution of PIM1 protease in mitochondria by Escherichia coli Lon protease. J Biol Chem 271 (17), pp. 10137 - 42 (1996)

Langer, T.; Buchner, J.; Bukau, B.: Chaperone function on Crete: a meeting report. Cell Stress Chaperones 1 (1), pp. 5 - 12 (1996)

Prip-Buus, C.; Westerman, B.; Schmitt, M.; Langer, T.; Neupert, W.; Schwarz, E.: Role of the mitochondrial DnaJ homologue, Mdj1p, in the prevention of heat-induced protein aggregation. FEBS Lett 380 (1-2), pp. 142 - 6 (1996)

Schmitt, M.; Neupert, W.; Langer, T.: Hsp78, a Clp homologue within mitochondria, can substitute for chaperone functions of mt-hsp70. EMBO J 14 (14), pp. 3434 - 44 (1995)

Langer, T.; Pajic, A.; Wagner, I.; Neupert, W.: Proteolytic breakdown of membrane-associated polypeptides in mitochondria of Saccharomyces cerevisiae. Methods Enzymol 260, pp. 495 - 503 (1995)