Department Langer

Journal Article (206)

2010
Journal Article
Lee, S.; Augustin, S.; Tatsuta, T.; Gerdes, F.; Langer, T.; Tsai, F. T.: Electron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease. J Biol Chem 286 (6), pp. 4404 - 11 (2010)
Journal Article
Brüning, J.; Langer, T.; Trifunovic, A.: Highlight: The biology of aging: mechanisms and intervention. Biol Chem 391 (10), p. 1113 (2010)
Journal Article
Potting, C.; Wilmes, C.; Engmann, T.; Osman, C.; Langer, T.: Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. EMBO J 29 (17), pp. 2888 - 98 (2010)
Journal Article
Osman, C.; Haag, M.; Wieland, F. T.; Brugger, B.; Langer, T.: A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29 (12), pp. 1976 - 87 (2010)
Journal Article
Di Bella, D.; Lazzaro, F.; Brusco, A.; Plumari, M.; Battaglia, G.; Pastore, A.; Finardi, A.; Cagnoli, C.; Tempia, F.; Frontali, M. et al.; Veneziano, L.; Sacco, T.; Boda, E.; Brussino, A.; Bonn, F.; Castellotti, B.; Baratta, S.; Mariotti, C.; Gellera, C.; Fracasso, V.; Magri, S.; Langer, T.; Plevani, P.; Di Donato, S.; Muzi-Falconi, M.; Taroni, F.: Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 42 (4), pp. 313 - 21 (2010)
Journal Article
Bonn, F.; Pantakani, K.; Shoukier, M.; Langer, T.; Mannan, A. U.: Functional evaluation of paraplegin mutations by a yeast complementation assay. Hum Mutat 31 (5), pp. 617 - 21 (2010)
2009
Journal Article
Ehses, S.; Raschke, I.; Mancuso, G.; Bernacchia, A.; Geimer, S.; Tondera, D.; Martinou, J. C.; Westermann, B.; Rugarli, E. I.; Langer, T.: Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J Cell Biol 187 (7), pp. 1023 - 36 (2009)
Journal Article
Osman, C.; Merkwirth, C.; Langer, T.: Prohibitins and the functional compartmentalization of mitochondrial membranes. J Cell Sci 122 (Pt 21), pp. 3823 - 30 (2009)
Journal Article
Tatsuta, T.; Langer, T.: AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines. Res Microbiol 160 (9), pp. 711 - 7 (2009)
Journal Article
Augustin, S.; Gerdes, F.; Lee, S.; Tsai, F. T.; Langer, T.; Tatsuta, T.: An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell 35 (5), pp. 574 - 85 (2009)
Journal Article
Koppen, M.; Bonn, F.; Ehses, S.; Langer, T.: Autocatalytic processing of m-AAA protease subunits in mitochondria. Mol Biol Cell 20 (19), pp. 4216 - 24 (2009)
Journal Article
Tondera, D.; Grandemange, S.; Jourdain, A.; Karbowski, M.; Mattenberger, Y.; Herzig, S.; Da Cruz, S.; Clerc, P.; Raschke, I.; Merkwirth, C. et al.; Ehses, S.; Krause, F.; Chan, D. C.; Alexander, C.; Bauer, C.; Youle, R.; Langer, T.; Martinou, J. C.: SLP-2 is required for stress-induced mitochondrial hyperfusion. EMBO J 28 (11), pp. 1589 - 600 (2009)
Journal Article
Osman, C.; Haag, M.; Potting, C.; Rodenfels, J.; Dip, P. V.; Wieland, F. T.; Brugger, B.; Westermann, B.; Langer, T.: The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184 (4), pp. 583 - 96 (2009)
2008
Journal Article
Merkwirth, C.; Langer, T.: Mitofusin 2 builds a bridge between ER and mitochondria. Cell 135 (7), pp. 1165 - 7 (2008)
Journal Article
Merkwirth, C.; Langer, T.: Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta 1793 (1), pp. 27 - 32 (2008)
Journal Article
Tatsuta, T.; Langer, T.: Studying proteolysis within mitochondria. Methods Mol Biol 372, pp. 343 - 60 (2008)
Journal Article
Merkwirth, C.; Dargazanli, S.; Tatsuta, T.; Geimer, S.; Lower, B.; Wunderlich, F. T.; von Kleist-Retzow, J. C.; Waisman, A.; Westermann, B.; Langer, T.: Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev 22 (4), pp. 476 - 88 (2008)
Journal Article
Tatsuta, T.; Langer, T.: Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 27 (2), pp. 306 - 14 (2008)
2007
Journal Article
Duvezin-Caubet, S.; Koppen, M.; Wagener, J.; Zick, M.; Israel, L.; Bernacchia, A.; Jagasia, R.; Rugarli, E. I.; Imhof, A.; Neupert, W. et al.; Langer, T.; Reichert, A. S.: OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell 18 (9), pp. 3582 - 90 (2007)
Journal Article
Koppen, M.; Langer, T.: Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases. Crit Rev Biochem Mol Biol 42 (3), pp. 221 - 42 (2007)
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