Publications

Naess, K.; Freyer, C.; Bruhn, H.; Wibom, R.; Malm, G.; Nennesmo, I.; von Dobeln, U.; Larsson, N.G.: MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome. Biochim Biophys Acta 1787 (5), pp. 484 - 90 (2008)

Aydin, J.; Andersson, D. C.; Hanninen, S. L.; Wredenberg, A.; Tavi, P.; Park, C. B.; Larsson, N.G.; Bruton, J. D.; Westerblad, H.: Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy. Hum Mol Genet 18 (2), pp. 278 - 88 (2008)

Stewart, J.; Freyer, C.; Elson, J. L.; Larsson, N.G.: Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease. Nat Rev Genet 9 (9), pp. 657 - 62 (2008)

Dufour, E.; Terzioglu, M.; Sterky, F. H.; Sorensen, L.; Galter, D.; Olson, L.; Wilbertz, J.; Larsson, N.G.: Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration. Hum Mol Genet 17 (10), pp. 1418 - 26 (2008)

Stewart, J.; Freyer, C.; Elson, J. L.; Wredenberg, A.; Cansu, Z.; Trifunovic, A.; Larsson, N.G.: Strong purifying selection in transmission of mammalian mitochondrial DNA. PLoS Biol 6 (1), p. e10 (2008)

Kukat, A.; Kukat, C.; Brocher, J.; Schafer, I.; Krohne, G.; Trounce, I. A.; Villani, G.; Seibel, P.: Generation of rho0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses. Nucleic Acids Res 36 (7), p. e44 (2008)

Seibel, P.; Di Nunno, C.; Kukat, C.; Schafer, I.; Del Bo, R.; Bordoni, A.; Comi, G. P.; Schon, A.; Capuano, F.; Latorre, D. et al.; Villani, G.: Cosegregation of novel mitochondrial 16S rRNA gene mutations with the age-associated T414G variant in human cybrids. Nucleic Acids Res 36 (18), pp. 5872 - 81 (2008)