Publications

Mourier, A.; Matic, S.; Ruzzenente, B.; Larsson, N.G.; Milenkovic, D.: The respiratory chain supercomplex organization is independent of COX7a2l isoforms. Cell Metab 20 (6), pp. 1069 - 75 (2014)

Baggio, F.; Bratic, A.; Mourier, A.; Kauppila, T. E. S.; Tain, L. S.; Kukat, C.; Habermann, B.H.; Partridge, L.; Larsson, N.G.: Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42 (22), pp. 13920 - 38 (2014)

Kühl, I.; Kukat, C.; Ruzzenente, B.; Milenkovic, D.; Mourier, A.; Miranda, M.; Koolmeister, C.; Falkenberg, M.; Larsson, N.G.: POLRMT does not transcribe nuclear genes. Nature 514 (7521), pp. E7 - 11 (2014)

Stewart, J.; Larsson, N.G.: Keeping mtDNA in shape between generations. PLoS Genet 10 (10), p. e1004670 (2014)

Hallberg , B. M.; Larsson, N.G.: Making proteins in the powerhouse. Cell Metab 20 (2), pp. 226 - 40 (2014)

Wilson, W. C.; Hornig-Do, H. T.; Bruni, F.; Chang, J. H.; Jourdain, A. A.; Martinou, J. C.; Falkenberg, M.; Spahr, H.; Larsson, N.G.; Lewis, R. J. et al.; Hewitt, L.; Basle, A.; Cross, H. E.; Tong, L.; Lebel, R. R.; Crosby, A. H.; Chrzanowska-Lightowlers, Z. M.; Lightowlers, R. N.: A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression. Hum Mol Genet 23 (23), pp. 6345 - 55 (2014)

Vernochet, C.; Damilano, F.; Mourier, A.; Bezy, O.; Mori, M. A.; Smyth, G.; Rosenzweig, A.; Larsson, N.G.; Kahn, C. R.: Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. Faseb j 28 (10), pp. 4408 - 19 (2014)

Li, L.; Trifunovic, A.; Kohler, M.; Wang, Y.; Petrovic Berglund, J.; Illies, C.; Juntti-Berggren, L.; Larsson, N.G.; Berggren, P. O.: Defects in beta-cell Ca2+ dynamics in age-induced diabetes. Diabetes 63 (12), pp. 4100 - 14 (2014)

Sharoyko, V. V.; Abels, M.; Sun, J.; Nicholas, L. M.; Mollet, I. G.; Stamenkovic, J. A.; Gohring, I.; Malmgren, S.; Storm, P.; Fadista, J. et al.; Spegel, P.; Metodiev, M. D.; Larsson, N.G.; Eliasson, L.; Wierup, N.; Mulder, H.: Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes. Hum Mol Genet 23 (21), pp. 5733 - 49 (2014)

Metodiev , M. D.; Spahr, H.; Loguercio Polosa, P.; Meharg, C.; Becker, C.; Altmueller, J.; Habermann, B.H.; Larsson, N.G.; Ruzzenente, B.: NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly. PLoS Genet 10 (2), p. e1004110 (2014)

Posse, V.; Hoberg, E.; Dierckx, A.; Shahzad, S.; Koolmeister, C.; Larsson, N.G.; Wilhelmsson, L. M.; Hallberg, B. M.; Gustafsson, C. M.: The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation. Nucleic Acids Res 42 (6), pp. 3638 - 47 (2014)

Mourier, A.; Ruzzenente, B.; Brandt, T.; Kuhlbrandt, W.; Larsson, N.G.: Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet 23 (10), pp. 2580 - 92 (2014)

Baines, H. L.; Stewart, J. B.; Stamp, C.; Zupanic, A.; Kirkwood, T. B. L.; Larsson, N.G.; Turnbull, D. M.; Greaves, L. C.: Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans. Mech. Ageing Dev. 139, pp. 22 - 30 (2014)

Hallberg, B. M.; Larsson, N.G.: Making proteins in the powerhouse. Cell Metab 20 (2), pp. 226 - 240 (2014)

Metodiev, M.D.; Spahr, H.; Polosa, P. L.; Meharg, C.; Becker, C.; Altmueller, J.; Habermann, B.H.; Larsson, N.G.; Ruzzenente, B.: NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly. PLOS GENETICS 10 (2), e1004110 (2014)

Sharoyko, V. V.; Abels, M.; Sun, J.; Nicholas, L. M.; Mollet, I. G.; Stamenkovic, J. A.; Göhring, I.; Malmgren, S.; Storm, P.; Fadista, J. et al.; Spégel, P.; Metodiev, M. D.; Larsson, N.G.; Eliasson, L.; Wierup, N.; Mulder, H.: Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes. Hum Mol Genet 23 (21), pp. 5733 - 5749 (2014)