Publications

Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams, S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (12), p. 1940 (2018)

Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams , S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (11), pp. 1696 - 1700 (2018)

Kauppila, T. E. S.; Bratic, A.; Jensen, M. B.; Baggio, F.; Partridge, L.; Jasper, H.; Grönke, S.; Larsson, N.G.: Mutations of mitochondrial DNA are not major contributors to aging of fruit flies. Proc Natl Acad Sci U S A 115 (41), pp. E9620 - E9629 (2018)

Spahr, H.; Chia, T.; Lingford, J. P.; Siira, S. J.; Cohen, S. B.; Filipovska, A.; Rackham, O.: Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nat Commun 9 (1), p. 2212 (2018)

Perks, K. L.; Rossetti, G.; Kuznetsova, I.; Hughes, L. A.; Ermer, J. A.; Ferreira, N.; Busch, J.; Rudler, D. L.; Spahr, H.; Schöndorf, T. et al.; Shearwood, A. J.; Viola, H. M.; Siira, S. J.; Hool, L. C.; Milenkovic, D.; Larsson, N.G.; Rackham, O.; Filipovska, A.: PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly. Cell Rep 23 (1), pp. 127 - 142 (2018)

Bonekamp, N.; Larsson, N.G.: SnapShot: Mitochondrial Nucleoid. Cell 172 (1-2), pp. 388 - 388 e1 (2018)

Nicholls, T. J.; Nadalutti, C. A.; Motori, E.; Sommerville, E. W.; Gorman, G. S.; Basu, S.; Hoberg, E.; Turnbull, D. M.; Chinnery, P. F.; Larsson, N.G. et al.; Larsson, E.; Falkenberg, M.; Taylor, R. W.; Griffith, J. D.; Gustafsson, C. M.: Topoisomerase 3alpha Is Required for Decatenation and Segregation of Human mtDNA. Mol Cell 69 (1), pp. 9 - 23 e6 (2018)

Kauppila, J. H. K.; Bonekamp, N.; Mourier, A.; Isokallio, M.; Just, A.; Kauppila, T.; Stewart, J.; Larsson, N.G.: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46 (13), pp. 6642 - 6669 (2018)

Matic, S.; Jiang, M.; Nicholls, T. J.; Uhler, J. P.; Dirksen-Schwanenland, C.; Polosa, P. L.; Simard, M.-L.; Li, X.; Atanassov, I.; Rackham, O. et al.; Filipovska, A.; Stewart, J.; Falkenberg, M.; Larsson, N.G.; Milenkovic, D.: Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9 (1), p. 1202 (2018)

Simard, M.-L.; Mourier, A.; Greaves, L. C.; Taylor, R. W.; Stewart, J.: A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol 245 (3), pp. 311 - 323 (2018)

Spåhr, H.; Chia, T.; Lingford, J. P.; Siira, S. J.; Cohen, S. B.; Filipovska, A.; Rackham, O.: Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nature Communications 9, 2212 (2018)