Publications of Ilian Atanassov

Cipullo, M.; Valentín Gesé, G.; Gopalakrishna, S.; Krueger, A.; Lobo, V.; Pirozhkova, M. A.; Marks, J.; Páleníková, P.; Shiriaev, D.; Liu, Y. et al.; Misic, J.; Cai, Y.; Nguyen, M. D.; Abdelbagi, A.; Li, X.; Minczuk, M.; Hafner, M.; Benhalevy, D.; Sarshad, A. A.; Atanassov, I.; Hällberg, B. M.; Rorbach, J.: GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nature Communications 15, 5664 (2024)

Kim, J. Y.; Atanassov, I.; Dethloff, F.; Kroczek, L.; Langer, T.: Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria. Life science alliance 6 (9), e202302127 (2023)

Remes , C.; Khawaja, A.; Pearce, S. F.; Dinan, A. M.; Gopalakrishna, S.; Cipullo, M.; Kyriakidis, V.; Zhang, J.; Dopico, X. C.; Yukhnovets, O. et al.; Atanassov, I.; Firth, A. E.; Cooperman, B.; Rorbach, J.: Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria. Nucleic Acids Research (2023)

Krüger, A.; Remes, C.; Shiriaev, D. I.; Liu, Y.; Spåhr, H.; Wibom, R.; Atanassov, I.; Nguyen, M. D.; Cooperman, B. S.; Rorbach, J.: Human mitochondria require mtRF1 for translation termination at non-canonical stop codons. Nature Communications 14, 30 (2023)

Milenkovic, D.; Misic, J.; Hevler, J. F.; Molinié, T.; Chung, I.; Atanassov, I.; Li, X.; Filograna, R.; Mesaros, A.; Mourier, A. et al.; Heck, A. J.R.; Hirst, J.; Larsson, N.-G.: Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes. Cell Metabolism (2023)

Itoh, Y.; Khawaja, A.; Laptev, I.; Cipullo, M.; Atanassov, I.; Sergiev, P.; Rorbach, J.; Amunts, A.: Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606 (7914), pp. 603 - 608 (2022)

Li, X.; Straub, J.; Medeiros, T. C.; Mehra, C.; den Brave, F.; Peker, E.; Atanassov, I.; Stillger, K.; Michaelis, J. B.; Burbridge, E. et al.; Adrain, C.; Munch, C.; Riemer, J.; Becker, T.; Pernas, L.: Mitochondria shed their outer membrane in response to infection-induced stress. Science 375 (6577), p. eabi4343 (2022)

Bonekamp, N.; Jiang, M.; Motori, E.; Garcia Villegas, R.; Koolmeister, C.; Atanassov, I.; Mesaros, A.; Park, C. B.; Larsson, N.G.: High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo. Life Sci Alliance 4 (11), p. e202101034 (2021)

Koester, J.; Miroshnikova, Y. A.; Ghatak, S.; Chacón-Martínez, C. A.; Morgner, J.; Li, X.; Atanassov, I.; Altmuller, J.; Birk, D. E.; Koch, M. et al.; Bloch, W.; Bartusel, M.; Niessen, C. M.; Rada-Iglesias, A.; Wickström, S. A.: Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol 23 (7), pp. 771 - 781 (2021)

Jiang, M.; Xie, X.; Zhu, X.; Jiang, S.; Milenkovic, D.; Misic, J.; Shi, Y.; Tandukar, N.; Li, X.; Atanassov, I. et al.; Jenninger, L.; Hoberg, E.; Albarran-Gutierrez, S.; Szilagyi, Z.; Macao, B.; Siira, S. J.; Carelli, V.; Griffith, J. D.; Gustafsson, C. M.; Nicholls, T. J.; Filipovska, A.; Larsson, N.G.; Falkenberg, M.: The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Sci Adv 7 (27), p. eabf8631 (2021)

Tain, L.; Sehlke, R.; Meilenbrock, R. L.; Leech, T.; Paulitz, J.; Chokkalingam, M.; Nagaraj, N.; Grönke, S.; Fröhlich, J.; Atanassov, I. et al.; Mann, M.; Beyer, A.; Partridge, L.: Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife 10 (2021)

Ruegenberg, S.; Mayr, F. A. M.C.; Atanassov, I.; Baumann, U.; Denzel, M.: Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun 12 (1), p. 2176 (2021)

Schober, F. A.; Atanassov, I.; Moore, D.; Calvo-Garrido, J.; Moedas, M. F.; Wedell, A.; Freyer, C.; Wredenberg, A.: Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits. Mol Cell Proteomics 20, p. 100065 (2021)

Schober, F. A.; Moore, D.; Atanassov, I.; Moedas, M. F.; Clemente, P.; Vegvari, A.; Fissi, N. E.; Filograna, R.; Bucher, A. L.; Hinze, Y. et al.; The, M.; Hedman, E.; Chernogubova, E.; Begzati, A.; Wibom, R.; Jain, M.; Nilsson, R.; Kall, L.; Wedell, A.; Freyer, C.; Wredenberg, A.: The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters. Sci Adv 7 (8) (2021)

Li, X.; Franz, T.; Atanassov, I.; Colby, T.: Step-by-Step Sample Preparation of Proteins for Mass Spectrometric Analysis. Methods Mol Biol 2261, pp. 13 - 23 (2021)

Schober, F. A.; Atanassov, I.; Freyer, C.; Wredenberg, A.: Quantitative Proteomics in Drosophila with Holidic Stable-Isotope Labeling of Amino Acids in Fruit Flies (SILAF). Methods Mol Biol 2192, pp. 75 - 87 (2021)

Bonekamp, N.; Peter, B.; Hillen, H. S.; Felser, A.; Bergbrede, T.; Choidas, A.; Horn, M.; Unger, A.; Di Lucrezia, R.; Atanassov, I. et al.; Li, X.; Koch, U.; Menninger, S.; Boros, J.; Habenberger, P.; Giavalisco, P.; Cramer, P.; Denzel, M. S.; Nussbaumer, P.; Klebl, B.; Falkenberg, M.; Gustafsson, C. M.; Larsson, N.G.: Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 588 (7839), pp. 712 - 716 (2020)

Cipullo, M.; Pearce, S. F.; Lopez Sanchez, I. G.; Gopalakrishna, S.; Kruger, A.; Schober, F.; Busch, J. D.; Li, X.; Wredenberg, A.; Atanassov, I. et al.; Rorbach, J.: Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49 (1), pp. 354 - 370 (2020)

Motori, E.; Atanassov, I.; Kochan, S. M. V.; Folz-Donahue, K.; Sakthivelu, V.; Giavalisco, P.; Toni, N.; Puyal, J.; Larsson, N.G.: Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction. Sci Adv 6 (35), p. eaba8271 (2020)

Tharyan, R. G.; Annibal, A.; Schiffer, I.; Laboy, R.; Atanassov, I.; Weber, A. L.; Gerisch, B.; Antebi, A.: NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin. Nat Metab 2 (5), pp. 387 - 396 (2020)