Marie Curie Fellowship awarded to Estelle Vincendeau

Research into the detection and repair of DNA damage

Estelle Vincendeau, Postdoc in the research group “Genome Instability and Ageing” of Stephanie Panier at the Max Planck Institute for Biology of Ageing, was awarded with the Marie Curie Research Fellowship. In her research she focuses on the mechanisms by which cells detect and repair DNA damage.

DNA breaks disrupt the physical continuity of the chromosomes and directly threaten genome integrity. To protect their genetic information, cells activate a complex signaling network which senses, signals and repairs DNA damage. Defects in this signaling network are associated to premature ageing syndromes and to ageing-associated diseases such as cancers and neurodegeneration.

“I am studying how cells respond to DNA damage”, explains Vincendeau. “Specifically, I am interested in the role of RNAs and RNA-binding proteins in the DNA repair process. The objectives of my research project will be to investigate the dynamics of RNA-binding proteins at DNA break sites, and to understand how these RNA-binding proteins process and regulate RNAs in the context of DNA damage.”

“I am delighted that the Marie Curie fellowship will allow me to pursue my research questions. It will help me develop my skill set and expand my scientific network. Stephanie Panier’s research group, expert in genome integrity, provides an ideal environment for this project”, says Vincendeau.

About the Marie Curie Research Fellowship

The Marie Curie research fellowships of the European Union are highly competitive. In addition to generous research funding, it gives scientists the possibility to gain experience abroad and to complete their training with competences or disciplines useful for their careers.

About Estelle Vincendeau

Estelle Vincendeau studied genetics at the Université Paris Cité and completed her PhD at the Institut Pasteur, Paris. In 2023, she joined the Research Group of Stephanie Panier at the Max Planck Institute for Biology of Ageing.

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