Department Langer

Journal Article (206)

2021
Journal Article
MacVicar, T.; Langer, T.: Mechanometabolism: Mitochondria promote resilience under pressure. Curr Biol 31 (13), pp. R859 - R861 (2021)
Journal Article
Sprenger, H.-G.; MacVicar, T.; Bahat, A.; Fiedler, K. U.; Hermans, S.; Ehrentraut, D.; Ried, K.; Milenkovic, D.; Bonekamp, N.; Larsson, N.G. et al.; Nolte, H.; Giavalisco, P.; Langer, T.: Cellular pyrimidine imbalance triggers mitochondrial DNA–dependent innate immunity. Nature Metabolism 3 (5), pp. 636 - 650 (2021)
2020
Journal Article
Wang, Z.; Liu, F.; Fan, N.; Zhou, C.; Li, D.; MacVicar, T.; Dong, Q.; Bruns, C. J.; Zhao, Y.: Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies. Front Oncol 10, p. 589508 (2020)
Journal Article
Mittenbühler, M. J.; Saedler, K.; Nolte, H.; Kern, L.; Zhou, J.; Qian, S. B.; Meder, L.; Ullrich, R. T.; Brüning, J. C.; Wunderlich, F. T.: Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Mol Metab 42, p. 101085 (2020)
Journal Article
Murschall, L. M.; Gerhards, A.; MacVicar, T.; Peker, E.; Hasberg, L.; Wawra, S.; Langer, T.; Riemer, J.: The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import. BMC Biol 18 (1), p. 96 (2020)
Journal Article
Deshwal, S.; Fiedler, K. U.; Langer, T.: Mitochondrial Proteases: Multifaceted Regulators of Mitochondrial Plasticity. Annu Rev Biochem 89, pp. 501 - 528 (2020)
Journal Article
Ohba, Y.; MacVicar, T.; Langer, T.: Regulation of mitochondrial plasticity by the i-AAA protease YME1L. Biol Chem 401 (6-7), pp. 877 - 890 (2020)
2019
Journal Article
Hahn, O.; Drews, L. F.; Nguyen, A.; Tatsuta, T.; Gkioni, L.; Hendrich, O.; Zhang, Q.; Langer, T.; Pletcher, S.; Wakelam, M. J. O. et al.; Beyer, A.; Grönke, S.; Partridge, L.: A nutritional memory effect counteracts benefits of dietary restriction in old mice. Nat Metab 1 (11), pp. 1059 - 1073 (2019)
Journal Article
MacVicar, T.; Ohba, Y.; Nolte, H.; Mayer, F. C.; Tatsuta, T.; Sprenger, H.-G.; Lindner, B.; Zhao, Y.; Li, J.; Bruns, C. et al.; Kruger, M.; Habich, M.; Riemer, J.; Schwarzer, R.; Pasparakis, M.; Henschke, S.; Bruning, J. C.; Zamboni, N.; Langer, T.: Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature 575 (7782), pp. 361 - 365 (2019)
Journal Article
Odendall, F.; Backes, S.; Tatsuta, T.; Weill, U.; Schuldiner, M.; Langer, T.; Herrmann, J. M.; Rapaport, D.; Dimmer, K. S.: The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism. Mol Biol Cell 30 (21), pp. 2681 - 2694 (2019)
Journal Article
Sprenger, H.-G.; Langer, T.: The Good and the Bad of Mitochondrial Breakups. Trends Cell Biol 29 (11), pp. 888 - 900 (2019)
Journal Article
Lill, R.; Langer, T.; Herrmann, J. M.: Walter Neupert (1939-2019), a pioneer of mitochondrial biogenesis and morphology. EMBO J 38 (17), p. e103100 (2019)
Journal Article
Ahola, S.; Langer, T.; MacVicar, T.: Mitochondrial Proteolysis and Metabolic Control. Cold Spring Harb Perspect Biol 11 (7) (2019)
Journal Article
Hammerschmidt, P.; Ostkotte, D.; Nolte, H.; Gerl, M. J.; Jais, A.; Brunner, H. L.; Sprenger, H.-G.; Awazawa, M.; Nicholls, H. T.; Turpin-Nolan, S. M. et al.; Langer, T.; Kruger, M.; Brugger, B.; Bruning, J. C.: CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell 177 (6), pp. 1536 - 1552 e23 (2019)
Journal Article
Murru, S.; Hess, S.; Barth, E.; Almajan, E. R.; Schatton, D.; Hermans, S.; Brodesser, S.; Langer, T.; Kloppenburg, P.; Rugarli, E. I.: Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia 67 (8), pp. 1526 - 1541 (2019)
Journal Article
Miliara, X.; Tatsuta, T.; Berry, J. L.; Rouse, S. L.; Solak, K.; Chorev, D. S.; Wu, D.; Robinson, C. V.; Matthews, S.; Langer, T.: Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun 10 (1), p. 1130 (2019)
Journal Article
Rashid, T.; Nemazanyy, I.; Paolini, C.; Tatsuta, T.; Crespin, P.; Villeneuve, D.; Brodesser, S.; Benit, P.; Rustin, P.; Baraibar, M. A. et al.; Agbulut, O.; Olivier, A.; Protasi, F.; Langer, T.; Chrast, R.; Lonlay, P.; Foucauld, H.; Blaauw, B.; Pende, M.: Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone‐responsive myopathy. The EMBO Journal 38 (2019)
2018
Journal Article
Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol 218 (2), pp. 598 - 614 (2018)
Journal Article
Patron, M.; Sprenger, H.-G.; Langer, T.: m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration. Cell Res 28 (3), pp. 296 - 306 (2018)
Journal Article
Brandt, C.; Nolte, H.; Henschke, S.; Engström Ruud, L.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. Cell 175, pp. 1321 - 1335.e20 (2018)
Go to Editor View