Publications of M. Horn

Kroef, V.; Ruegenberg, S.; Horn, M.; Allmeroth, K.; Ebert, L.; Bozkus, S.; Miethe, S.; Elling, U.; Schermer, B.; Baumann, U. et al.; Denzel, M. S.: GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife 11 (2022)

Bonekamp, N.; Peter, B.; Hillen, H. S.; Felser, A.; Bergbrede, T.; Choidas, A.; Horn, M.; Unger, A.; Di Lucrezia, R.; Atanassov, I. et al.; Li, X.; Koch, U.; Menninger, S.; Boros, J.; Habenberger, P.; Giavalisco, P.; Cramer, P.; Denzel, M. S.; Nussbaumer, P.; Klebl, B.; Falkenberg, M.; Gustafsson, C. M.; Larsson, N.G.: Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 588 (7839), pp. 712 - 716 (2020)

Allmeroth, K.; Horn, M.; Kroef, V.; Miethe, S.; Muller, R. U.; Denzel, M. S.: Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia 35 (3), pp. 887 - 892 (2020)

Horn, M.; Denzel, S. I.; Srinivasan, B.; Allmeroth, K.; Schiffer, I.; Karthikaisamy, V.; Miethe, S.; Breuer, P.; Antebi, A.; Denzel, M. S.: Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response. iScience 23 (3), p. 100887 (2020)

Ruegenberg, S.; Horn, M.; Pichlo, C.; Allmeroth, K.; Baumann, U.; Denzel, M. S.: Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun 11 (1), p. 687 (2020)

Saez, I.; Gerbracht, J. V.; Koyuncu, S.; Lee, H. J.; Horn, M.; Kroef, V.; Denzel, M. S.; Dieterich, C.; Gehring, N. H.; Vilchez, D.: The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells. FEBS Lett 594 (1), pp. 175 - 188 (2019)

Horn, M.; Metge, F.; Denzel, M. S.: Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug-Target Interactions. Methods Mol Biol 1953, pp. 23 - 31 (2019)

Horn, M.; Kroef, V.; Allmeroth, K.; Schuller, N.; Miethe, S.; Peifer, M.; Penninger, J. M.; Elling, U.; Denzel, M. S.: Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells. Oncotarget 9 (11), pp. 9838 - 9851 (2018)

Horn, M.; Geisen, C.; Cermak, L.; Becker, B.; Nakamura, S.; Klein, C.; Pagano, M.; Antebi, A.: DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation. Dev Cell 28 (6), pp. 697 - 710 (2014)