External Member: Larsson Adjunct Group

Journal Article (201)

2019
Journal Article
Busch, J.; Cipullo, M.; Atanassov, I.; Bratic, A.; Ramos, E.S.; Schöndorf, T.; Li, X.; Pearce, S. F.; Milenkovic, D.; Rorbach, J. et al.; Larsson, N.G.: MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition. Cell Rep 29 (6), pp. 1728 - 1738 e9 (2019)
Journal Article
Nicholls, T. J.; Spahr, H.; Jiang, S.; Siira, S. J.; Koolmeister, C.; Sharma, S.; Kauppila, J. H. K.; Jiang, M.; Kaever, V.; Rackham, O. et al.; Chabes, A.; Falkenberg, M.; Filipovska, A.; Larsson, N.G.; Gustafsson, C. M.: Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol Cell 76 (5), pp. 784 - 796 e6 (2019)
Journal Article
Gopalakrishna, S.; Pearce, S. F.; Dinan, A. M.; Schober, F. A.; Cipullo, M.; Spahr, H.; Khawaja, A.; Maffezzini, C.; Freyer, C.; Wredenberg, A. et al.; Atanassov, I.; Firth, A. E.; Rorbach, J.: C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis. Nucleic Acids Res 47 (17), pp. 9386 - 9399 (2019)
Journal Article
Ramos, E.S.; Motori, E.; Bruser, C.; Kuhl, I.; Yeroslaviz, A.; Ruzzenente, B.; Kauppila, J. H. K.; Busch, J.; Hultenby, K.; Habermann, B. H. et al.; Jakobs, S.; Larsson, N.G.; Mourier, A.: Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS Genet 15 (6), p. e1008085 (2019)
Journal Article
Jiang, M.; Koolmeister, C.; Misic, J.; Siira, S.; Kuhl, I.; Silva Ramos, E.; Miranda, M.; Jiang, M.; Posse, V.; Lytovchenko, O. et al.; Atanassov, I.; Schober, F. A.; Wibom, R.; Hultenby, K.; Milenkovic, D.; Gustafsson, C. M.; Filipovska, A.; Larsson, N.G.: TEFM regulates both transcription elongation and RNA processing in mitochondria. EMBO Rep 20 (6) (2019)
Journal Article
Filograna, R.; Koolmeister, C.; Upadhyay, M.; Pajak, A.; Clemente, P.; Wibom, R.; Simard, M. L.; Wredenberg, A.; Freyer, C.; Stewart, J. et al.; Larsson, N.G.: Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse. Sci Adv 5 (4), p. eaav9824 (2019)
Journal Article
Rangaraju, V.; Lewis, T. L.,. J.; Hirabayashi, Y.; Bergami, M.; Motori, E.; Cartoni, R.; Kwon, S. K.; Courchet, J.: Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease. J Neurosci 39 (42), pp. 8200 - 8208 (2019)
2018
Journal Article
Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams, S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (12), p. 1940 (2018)
Journal Article
Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams , S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (11), pp. 1696 - 1700 (2018)
Journal Article
Kauppila, T. E. S.; Bratic, A.; Jensen, M. B.; Baggio, F.; Partridge, L.; Jasper, H.; Grönke, S.; Larsson, N.G.: Mutations of mitochondrial DNA are not major contributors to aging of fruit flies. Proc Natl Acad Sci U S A 115 (41), pp. E9620 - E9629 (2018)
Journal Article
Spahr, H.; Chia, T.; Lingford, J. P.; Siira, S. J.; Cohen, S. B.; Filipovska, A.; Rackham, O.: Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nat Commun 9 (1), p. 2212 (2018)
Journal Article
Perks, K. L.; Rossetti, G.; Kuznetsova, I.; Hughes, L. A.; Ermer, J. A.; Ferreira, N.; Busch, J.; Rudler, D. L.; Spahr, H.; Schöndorf, T. et al.; Shearwood, A. J.; Viola, H. M.; Siira, S. J.; Hool, L. C.; Milenkovic, D.; Larsson, N.G.; Rackham, O.; Filipovska, A.: PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly. Cell Rep 23 (1), pp. 127 - 142 (2018)
Journal Article
Bonekamp, N.; Larsson, N.G.: SnapShot: Mitochondrial Nucleoid. Cell 172 (1-2), pp. 388 - 388 e1 (2018)
Journal Article
Nicholls, T. J.; Nadalutti, C. A.; Motori, E.; Sommerville, E. W.; Gorman, G. S.; Basu, S.; Hoberg, E.; Turnbull, D. M.; Chinnery, P. F.; Larsson, N.G. et al.; Larsson, E.; Falkenberg, M.; Taylor, R. W.; Griffith, J. D.; Gustafsson, C. M.: Topoisomerase 3alpha Is Required for Decatenation and Segregation of Human mtDNA. Mol Cell 69 (1), pp. 9 - 23 e6 (2018)
Journal Article
Kauppila, J. H. K.; Bonekamp, N.; Mourier, A.; Isokallio, M.; Just, A.; Kauppila, T.; Stewart, J.; Larsson, N.G.: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46 (13), pp. 6642 - 6669 (2018)
Journal Article
Matic, S.; Jiang, M.; Nicholls, T. J.; Uhler, J. P.; Dirksen-Schwanenland, C.; Polosa, P. L.; Simard, M.-L.; Li, X.; Atanassov, I.; Rackham, O. et al.; Filipovska, A.; Stewart, J.; Falkenberg, M.; Larsson, N.G.; Milenkovic, D.: Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9 (1), p. 1202 (2018)
Journal Article
Simard, M.-L.; Mourier, A.; Greaves, L. C.; Taylor, R. W.; Stewart, J.: A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol 245 (3), pp. 311 - 323 (2018)
Journal Article
Spåhr, H.; Chia, T.; Lingford, J. P.; Siira, S. J.; Cohen, S. B.; Filipovska, A.; Rackham, O.: Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins. Nature Communications 9, 2212 (2018)
2017
Journal Article
Siira, S. J.; Spahr, H.; Shearwood, A. J.; Ruzzenente, B.; Larsson, N.G.; Rackham, O.; Filipovska, A.: LRPPRC-mediated folding of the mitochondrial transcriptome. Nat Commun 8 (1), p. 1532 (2017)
Journal Article
Kühl, I.; Miranda, M.; Atanassov, I.; Kuznetsova, I.; Hinze, Y.; Mourier, A.; Filipovska, A.; Larsson, N.G.: Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. Elife 6 (2017)
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